Duovir-E Kit (Lamivudine/Zidovudine/Efavirenz)

Duovir E Kit Tablet contains the active ingredient Efavirenz + Lamivudine + Zidovudine. It is a combination of three antiretroviral medicines. Lamivudine, Zidovudine belong to the class of medications called nucleoside/nucleotide reverse transcriptase inhibitors. Efavirenz belongs to the class of medication called non-nucleoside reverse transcriptase inhibitors. It is used to treat HIV-1 infection. It mainly occurs when a person's immune system is attacked and weakened by the human immunodeficiency virus (HIV). This infection progressively weakens the immune system, making individuals more susceptible to opportunistic infections

This drug is contraindicated in individuals with severe renal impairment and may have altered drug clearance, which mainly affects the efficacy and safety of the medicine. Also, it is highly advised not to use this drug in patients with severe renal impairment. Dose adjustment is necessary for such conditions. Tell your doctor if you have any liver disease, including hepatitis B or C, kidney disease, heart problems, diabetes, history of seizures, mental health problems, consumed street drugs, or large amounts of alcohol before taking Duovir E Kit Tablet. The administration of this medicine is associated with hematologic toxicity (decrease in blood cells), muscle weakness, liver diseases, infection, and lactic acidosis (acid buildup due to problems in the body's metabolism). Do not breastfeed. Consult your doctor about safe sex practices

Treatment of HIV -1 infection

Duovir E Kit Tablet is a combination of three antiretroviral medicines. It works by inhibiting the enzyme reverse transcriptase, thereby inhibiting the replication of viral particles in the body and treating the infection

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications, including Trimethoprim/sulfamethoxazole, zalcitabine, Co-administration of ganciclovir, interferon-alpha, and stavudine, may interact with Duovir E Kit Tablet and reduce its effectiveness by causing undesirable side effects

• Store Duovir E Kit Tablet at (20°C to 25°C).
• Keep the medicine out of reach of children and pets

Take the Duovir E Kit Tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.