Axentri 150mg Tablets (Maraviroc)

Axentri 150mg Tablets are an antiretroviral drug belonging to the chemokine receptor antagonist category, containing the active ingredient Maraviroc. It is used to treat only CCR5-tropic human immunodeficiency virus type 1 (HIV-1) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken in combination with other medicines used to treat HIV infection

This drug is contraindicated in individuals with severe renal impairment and may have altered drug clearance, which mainly affects the efficacy and safety of the medicine. Also, it is highly advised not to use this drug in patients with severe renal impairment. Dose adjustment is necessary for such conditions. The liver metabolizes this medicine, specifically through the cytochrome P450 enzyme. In patients with liver impairment, the clearance of Axentri 150mg Tablet may be reduced, leading to increased drug concentrations in the bloodstream. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual.

Treatment of HIV – 1 infection

Axentri 150mg Tablet blocks a receptor named CCR5, which HIV uses to enter and infect your blood cells. This drug mainly prevents HIV from binding to and entering the CD4+ T cells, inhibiting the virus's ability to replicate and spread

Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications, such as efavirenz, may interact with Axentri 150mg Tablet and reduce effectiveness by causing undesirable side effects.

• Store Axentri 150mg Tablet at room temperature (15°to 25°C).
• Keep the tablet out of reach of children and pets.

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take a Axentri 150mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the tablet. Swallow the whole tablet with water